Design of pharmaceutical facilities is governed by Good Manufacturing Practices (GMP's), which require companies to document how they intend to design and operate their facility. These are intended to set forth engineering requirements deemed necessary for safe design and operation of pharmaceutical facilities. Failure to comply puts the owner at both regulatory and business risk and therefore it is important that the pharmaceutical facilities are constructed under a rigorous and well-defined quality-control system.
Pharmaceutical manufacturing is generally conducted in environments that are cleaner and are carefully controlled at a required temperature, humidity and pressure. The HVAC system assumes a large part of the responsibility in maintaining these clean environments.